Journal: Biomedical Optics Express
Article Title: Multi-parametric functional optical spectroscopy to monitor the metabolic and vascular changes in small head and neck tumors in vivo with radiation stress
doi: 10.1364/BOE.565339
Figure Lengend Snippet: ( A ) Representative SCC-61 and rSCC-61 tumors measured by our optical spectroscopy; ( B ) Tumor volumes of SCC-61 and rSCC-61 tumors on day 10 post cell injection; ( C ) Average diffuse reflectance spectra measured on all five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( D ) MC model extracted absorption coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors; ( E ) MC model extracted reduced scattering coefficients of five in vivo SCC-61 tumors and five in vivo rSCC-61 tumors. Tumor volume was estimated using the equation: volume = (Length x Width x Height)/2.
Article Snippet: All raw diffuse reflectance spectra were calibrated using a 20% reflectance standard (Spectralon, Labsphere) before quantitative analysis.
Techniques: Spectroscopy, Injection, In Vivo